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Our offerings are designed to inform key commercialization decisions.

Clinical Development Timeline

How big is our market?

  • “Water-fall” slides estimating accessible opportunity and “leakages” in each leverage point
  • Robust estimates of dynamic (e.g., incidence) and static (e.g., prevalence) patient pools
  • Population modeling to understand long-term trends, impact of anticipated shifts

How we derive REAL insights:

  • We integrate multiple data sources and are knowledgeable about each individual dataset's limitations and the ways of overcoming them
  • We leverage our patient flow modeling platform to develop Disease Natural History Models to cross-validate epi estimates and create a non-conflicting view of TA evolution

Clinical Development Timeline

Where should we focus?

  • Diagram describing the entire care continuum and highlighting important factors influencing care and outcomes
  • Prioritized list of influence points, behavioral objectives and drivers / barriers for our brand

How we derive REAL insights:

  • We go beyond simply diagramming to quantify the key elements of the journey
  • We integrate insights from quant (e.g., claims, charts, etc.) and qual (e.g., emotional journey)
  • We develop multiple versions, e.g., highly-detailed and quantified (for market researchers), as well as high-level visual infographics (for leadership, publications, etc.)

Clinical Development Timeline

What drives treatment choice?

  • Statistical data mining analysis to identify drivers of choice and key patient types treated differently
  • Decision algorithm based on the most important characteristics influencing treatment selection

How we derive REAL insights:

  • We use multiple algorithms and validate decision logic and resulting patient types with qual. research and feedback from Medical
  • ViewFinder™ research platform enables us to analyze current and future decision making
  • We create effective diagrams communicating key insights in an intuitive story-telling format

Clinical Development Timeline

Where is our opportunity?

  • Clear, actionable and enduring “bird's-eye” view of the opportunity space and playing fields available to our drug

How we derive REAL insights:

  • Optimal market map design combines data-derived drivers with qual. insights and strategic thinking from the brand team
  • ViewFinder™ research platform enables us to populate the map with projected sizes and overlay our drug's ability to win

Clinical Development Timeline

What are the key market sub-groups?

  • Divides target prescribers into like sub-groups aligned by attitudes, motivations, perceptions and behaviors
  • Considers multiple segmentation techniques and solutions:
    • Simpler rules-based algorithms generally preferred as they are easier to understand / communicate
    • Regression-based approaches offer more power and typically higher predictive accuracy but require more effort to explain
  • Based on choices and inferred preferences vs. stated answers

How we derive REAL insights:

  • We leverage all available data (e.g., survey responses, patient charts/cases, linked secondary data, etc.) to enhance understanding
  • We perform comprehensive data-mining to uncover segment insights
  • We utilize both univariate and multi-variate statistical techniques
  • We conduct qualitative reconnects to further validate and add color/depth
  • We connect segments to target list CRM eliminating need for typing tools making sales reps’ jobs easier, not harder

Clinical Development Timeline

What's our peak share?

  • Preference share
  • Share validation and discounting
  • Sensitivity to scenarios
  • Source of business / regimens displaced
  • Optimal sequencing
  • Drivers / barriers
  • Target patient and physician types
  • User-friendly simulator

How we derive REAL insights

  • We have developed proprietary chart-based TPP exposure and testing methodologies which result in robust and realistic estimates of clinical preference and deep understanding of what is driving the share
  • ShareCaster™ research platform enables us to accommodate a large range of scenarios and conjoint designs without fatiguing respondents and compromising the quality of the data

Clinical Development Timeline

What drives share?

  • Understand the evolution of brand preference and current reasons for brand selection by prescribers
  • Assess the existing market’s unmet needs and remaining areas for improvement

How we derive REAL insights

  • We design primary market research to maximize each respondents’ contributions which boosts statistical power and decreases costs
  • We utilize intuitive chose tasks which result in higher quality data vs. the repetitive rating exercises
  • We field multi-wave quant studies with patient cases which increases the stability of results and enables analysis over time and by sub-segment

Clinical Development Timeline

How do we track our launch?

  • Bottom-up patient based vs. top-down share gain models
  • Dynamic with DIY user interface to adjust inputs and enable scenario modeling
  • Outputs can be portrayed in either patients, pills, doses, or revenue

How we derive REAL insights

  • We account for patient flow dynamics to ensure share calls are only applied to in-play patients – this helps ensure brand uptake assumptions are possible to achieve and the uptake curves are governed by market dynamics
  • We explicitly track treatment experience overtime to account for cross-line reduction and to better quantify opportunities by prior treatment profile
  • We use meaningful patient cohorts which present distinct opportunities to the brand
  • We cross-validate input assumptions and output trends using data points from literature, PMR, and secondary data analytics

Clinical Development Timeline

SAPPHIRE™ Platform / SAPPHIRE™ Syndicated

  • Chart-based tracking platform designed to deliver clear, actionable insight into bio-pharmaceutical brand performance on a global basis
  • Modular platform covering key performance metrics – awareness, perceptions, share, behaviors, message recall & sales force effectiveness

How we derive REAL insights

  • A unified view of brand health combining attitudinal data from quant with behavioral insights from patient charts and claims data
  • We align KPIs logically to the adoption cascade to enable timely identification of bottlenecks post-launch
  • Global coverage provides insight at the local market level as well as a global view of key indicators of brand performance
  • Unique IDs link respondents across modules, disease states (e.g. tumor types or LoT) and waves enabling tracking for longitudinal analysis

SAPPHIRE™ is available both as a custom platform or as a syndicated report in select TAs and Markets

Contact Us

Email

info@michaelallencompany.com

Phone

+1.203.662.5100

Fax

+1.203.662.5180

Address

30 Old Kings Highway South
Darien, CT
06820

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